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Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats | Scientific Reports
AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice | Communications Biology
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology | Nature Communications
Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology | Nature Communications
Frontiers | The Role of Ceramides in Insulin Resistance
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure | Nature Communications
The role of ceramides in metabolic disorders: when size and localization matters | Nature Reviews Endocrinology
Role of ceramides in the pathogenesis of diabetes mellitus and its complications - ScienceDirect
Nutrients | Free Full-Text | Lipid-Induced Insulin Resistance in Skeletal Muscle: The Chase for the Culprit Goes from Total Intramuscular Fat to Lipid Intermediates, and Finally to Species of Lipid Intermediates
Ceramides are early responders in metabolic syndrome development in rhesus monkeys | Scientific Reports
Ceramides are early responders in metabolic syndrome development in rhesus monkeys | Scientific Reports
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The role of ceramides in metabolic disorders: when size and localization matters | Nature Reviews Endocrinology
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism | Nature Communications
Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance | Nature Communications
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet | International Journal of Obesity
Frontiers | The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications